preprocess
Description
Pre-processes data Computes QTcB, QTcF, deltaQTcF, deltaQTcB, deltaHR, deltaQTcB Baseline Mean, deltaQTcF Baseline Mean, deltaHR Baseline Mean
Usage
preprocess( data)Arguments
| Name | Description |
|---|---|
data | Data frame containing QTc data |
Returns
dataframe with deltas computed from BL
Examples
preprocess(data)# A tibble: 643 × 30 ID TRTG DOSE DOSEU DOSEF NTLD TAFD CONC CONCU RR HR QT RRBL <dbl> <fct> <dbl> <chr> <fct> <dbl> <chr> <dbl> <chr> <dbl> <dbl> <dbl> <dbl> 1 1001 Plac… 0 mg 0 mg 0.5 0.5 … 0 <NA> 968 62.0 381. 851 2 1002 Plac… 0 mg 0 mg 0.5 0.5 … 0 <NA> 1097. 54.7 405. 1193. 3 1003 Plac… 0 mg 0 mg 0.5 0.5 … 0 <NA> 1026. 58.5 394. 923. 4 1004 Plac… 0 mg 0 mg 0.5 0.5 … 0 <NA> 862. 69.6 396. 883. 5 1005 Plac… 0 mg 0 mg 0.5 0.5 … 0 <NA> 1060. 56.6 398 1126. 6 1006 Plac… 0 mg 0 mg 0.5 0.5 … 0 <NA> 998 60.2 385 999 7 1007 Plac… 0 mg 0 mg 0.5 0.5 … 0 <NA> 919. 65.4 399. 909 8 1008 Plac… 0 mg 0 mg 0.5 0.5 … 0 <NA> 827. 72.5 371 991 9 1009 Plac… 0 mg 0 mg 0.5 0.5 … 0 <NA> 872. 68.9 368. 798.10 1010 Plac… 0 mg 0 mg 0.5 0.5 … 0 <NA> 1070. 56.1 424. 1071# ℹ 633 more rows# ℹ 17 more variables: HRBL <dbl>, QTBL <dbl>, QTCB <dbl>, QTCBBL <dbl>,# QTCF <dbl>, QTCFBL <dbl>, HRBLM <dbl>, deltaHRBL <dbl>, QTCBBLM <dbl>,# deltaQTCBBL <dbl>, QTCFBLM <dbl>, deltaQTCFBL <dbl>, deltaQTCB <dbl>,# deltaQTCF <dbl>, deltaRR <dbl>, deltaHR <dbl>, deltaQT <dbl>