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cqtkit

compute_delta_qtcbblm

Description

Computes Baseline Mean QTCB

Usage

compute_delta_qtcbblm(
  data,
  id_col = ID,
  qtcbbl_col = QTCBBL,
  deduplicate = TRUE
)

Arguments

NameDescription
datadataframe of input data
id_colan unquoted column name of ID data
qtcbbl_colan unquoted column name of baseline QTCB measurements, default is QTCBBL
deduplicateboolean, whether baseline values are duplicated over rows. If true duplicates will be removed from average

Returns

a dataframe with deltaQTCBBL column

Examples

compute_delta_qtcbblm(compute_qtcb_qtcf(data))
compute_qtcbblm_delta.R
# A tibble: 643 × 21
      ID TRTG   DOSE DOSEU DOSEF  NTLD TAFD   CONC CONCU    RR    HR    QT  RRBL
   <dbl> <fct> <dbl> <chr> <fct> <dbl> <chr> <dbl> <chr> <dbl> <dbl> <dbl> <dbl>
 1  1001 Plac…     0 mg    0 mg    0.5 0.5 …     0 <NA>   968   62.0  381.  851
 2  1002 Plac…     0 mg    0 mg    0.5 0.5 …     0 <NA>  1097.  54.7  405. 1193.
 3  1003 Plac…     0 mg    0 mg    0.5 0.5 …     0 <NA>  1026.  58.5  394.  923.
 4  1004 Plac…     0 mg    0 mg    0.5 0.5 …     0 <NA>   862.  69.6  396.  883.
 5  1005 Plac…     0 mg    0 mg    0.5 0.5 …     0 <NA>  1060.  56.6  398  1126.
 6  1006 Plac…     0 mg    0 mg    0.5 0.5 …     0 <NA>   998   60.2  385   999
 7  1007 Plac…     0 mg    0 mg    0.5 0.5 …     0 <NA>   919.  65.4  399.  909
 8  1008 Plac…     0 mg    0 mg    0.5 0.5 …     0 <NA>   827.  72.5  371   991
 9  1009 Plac…     0 mg    0 mg    0.5 0.5 …     0 <NA>   872.  68.9  368.  798.
10  1010 Plac…     0 mg    0 mg    0.5 0.5 …     0 <NA>  1070.  56.1  424. 1071
# ℹ 633 more rows
# ℹ 8 more variables: HRBL <dbl>, QTBL <dbl>, QTCB <dbl>, QTCF <dbl>,
#   QTCBBL <dbl>, QTCFBL <dbl>, QTCBBLM <dbl>, deltaQTCBBL <dbl>